Invention Grant
- Patent Title: Protected diols for prostaglandin synthesis
- Patent Title (中): 用于前列腺素合成的保护性二醇
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Application No.: US11327876Application Date: 2006-01-09
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Publication No.: US07161042B2Publication Date: 2007-01-09
- Inventor: Derek Wyndham Clissold , Stuart Wilbert Craig , Rajendrakumar Reddy Gadikota , Min He , Jurjus Fayez Jurayj , Shahrokh Kazerani , Erwin Rannala , Pradeep Kumar Sharma
- Applicant: Derek Wyndham Clissold , Stuart Wilbert Craig , Rajendrakumar Reddy Gadikota , Min He , Jurjus Fayez Jurayj , Shahrokh Kazerani , Erwin Rannala , Pradeep Kumar Sharma
- Applicant Address: GB London
- Assignee: Johnson Matthey Public Limited Company
- Current Assignee: Johnson Matthey Public Limited Company
- Current Assignee Address: GB London
- Agency: RatnerPrestia
- Main IPC: C07C45/00
- IPC: C07C45/00 ; C07C41/00 ; C07C35/06 ; C07D311/92 ; C07D307/87
Abstract:
A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR′ wherein n is an integer from 1 to 3 and R′ represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR″ and NHR″ wherein R″ is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.
Public/Granted literature
- US20060106235A1 Protected diols for prostaglandin synthesis Public/Granted day:2006-05-18
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