发明授权
US07166596B2 Heterocyclic aromatic compounds useful as growth hormone secretagogues
有权
用作生长激素促分泌素的杂环芳族化合物
- 专利标题： Heterocyclic aromatic compounds useful as growth hormone secretagogues
- 专利标题（中）： 用作生长激素促分泌素的杂环芳族化合物
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申请号： US10653410申请日： 2003-09-02
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公开(公告)号： US07166596B2公开(公告)日： 2007-01-23
- 发明人: Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
- 申请人： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Co.
- 当前专利权人： Bristol-Myers Squibb Co.
- 当前专利权人地址： US NJ Princeton
- 代理商 Sammy G. Duncan, Jr.
- 主分类号： C07D221/00
- IPC分类号： C07D221/00 ; A61K31/395
摘要：
Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.