- 专利标题： Thiazolyl-based compounds useful as kinase inhibitors
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申请号： US10773790申请日： 2004-02-06
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公开(公告)号： US07169771B2公开(公告)日： 2007-01-30
- 发明人: John Hynes , Hong Wu , Katerina Leftheris , Chunjian Liu , Jagabandhu Das , Robert V. Moquin
- 申请人： John Hynes , Hong Wu , Katerina Leftheris , Chunjian Liu , Jagabandhu Das , Robert V. Moquin
- 申请人地址： US NJ Princton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princton
- 代理商 Joseph C. Wang; Anastasia P. Winslow
- 主分类号： A61K31/425
- IPC分类号： A61K31/425 ; C07D277/20
摘要：
The present invention provides thiazolyl-based compounds of formula (I), useful for treating p38 kinase-associated conditions, wherein ring A is phenyl or pyridyl, and X, Y, B, R2, R3, Z1 m and n are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
公开/授权文献
- US20040220233A1 Thiazolyl-based compounds useful as kinase inhibitors 公开/授权日：2004-11-04
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