Invention Grant
US07183291B2 Method for the treatment of malaria by the use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4- (6-methoxy-8-quinolinyl)-1,4-pentanediamine as gametocytocidal agent
有权
通过使用伯氨基衍生物N1-(3-乙基吡啶四氢呋喃-2-酮)-N4-(6-甲氧基-8-喹啉基)-1,4-戊二胺作为杀青霉素剂治疗疟疾的方法
- Patent Title: Method for the treatment of malaria by the use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4- (6-methoxy-8-quinolinyl)-1,4-pentanediamine as gametocytocidal agent
- Patent Title (中): 通过使用伯氨基衍生物N1-(3-乙基吡啶四氢呋喃-2-酮)-N4-(6-甲氧基-8-喹啉基)-1,4-戊二胺作为杀青霉素剂治疗疟疾的方法
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Application No.: US09316313Application Date: 1999-05-21
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Publication No.: US07183291B2Publication Date: 2007-02-27
- Inventor: Ram Pratap , Amiya Prasad Bhaduri , Harsh Pati Thapliyal , Sunil Kumar Puri , Guru Prasad Dutta , Anil Kumar Dwivedi , Satyawan Singh , Pratima Srivastava , Vikash Chandra Pandey , Sudhir Srivastava , Shio Kumar Singh , Ram Chandra Gupta , Jagdishwar Sahai Srivastava , Omkar Prasad Asthana
- Applicant: Ram Pratap , Amiya Prasad Bhaduri , Harsh Pati Thapliyal , Sunil Kumar Puri , Guru Prasad Dutta , Anil Kumar Dwivedi , Satyawan Singh , Pratima Srivastava , Vikash Chandra Pandey , Sudhir Srivastava , Shio Kumar Singh , Ram Chandra Gupta , Jagdishwar Sahai Srivastava , Omkar Prasad Asthana
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific and Industrial Research
- Current Assignee: Council of Scientific and Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Ladas and Parry LLP
- Priority: IN655/DEL/99 19990429
- Main IPC: C07D215/38
- IPC: C07D215/38 ; A61K31/4709

Abstract:
The present invention a novel use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine in the treatment and controlling the spread of malaria. In particular, the present invention discloses a method of treatment of malaria by the use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine as a gametocytocidal agent.
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