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发明授权
US07192971B2 4-Heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein 失效
4-杂芳基四氢喹啉及其作为胆固醇酯转移蛋白的抑制剂的用途

4-Heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
摘要：
Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
摘要（中）：

异四氢喹啉可以通过将相应取代的杂四氢喹啉醛与所需的取代基缩合或通过还原相应的酮取代的杂四氢喹啉来制备，然后通过常规方法引入所需的取代基。 杂四氢喹啉适合用作药物中的活性化合物，特别是用于治疗动物硬化和血脂异常的药物。

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