Invention Grant
US07217813B2 Methods for labeling nucleotides, labeled nucleotides and useful intermediates
有权
标记核苷酸，标记核苷酸和有用中间体的方法
- Patent Title: Methods for labeling nucleotides, labeled nucleotides and useful intermediates
- Patent Title (中): 标记核苷酸，标记核苷酸和有用中间体的方法
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Application No.: US10950985Application Date: 2004-09-27
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Publication No.: US07217813B2Publication Date: 2007-05-15
- Inventor: Hendrick Jan Houthoff , Jan Reedijk , Tinka Jelsma , Robert Jochem Heetebrij , Herman Hendricus Volkers
- Applicant: Hendrick Jan Houthoff , Jan Reedijk , Tinka Jelsma , Robert Jochem Heetebrij , Herman Hendricus Volkers
- Applicant Address: NL Amsterdam
- Assignee: Kreatech Biotechnology B.V.
- Current Assignee: Kreatech Biotechnology B.V.
- Current Assignee Address: NL Amsterdam
- Agency: Hoffmann & Baron, LLP
- Priority: EP96202792 19961008
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C07H19/04 ; C12Q1/68 ; G01N33/53
Abstract:
The present invention provides a labeled nucleoside having formula: where X represents an aliphatic diamine, and the labeling moiety comprises a label and a spacer, where the spacer is coupled at one end to a platinum atom and at the other end to the label, which spacer comprises a chain having at least four carbon atoms and at least one oxygen atom in the chain. The invention further provides a method for labeling a nucleoside, kits for labeling a nucleoside, and kits for producing a labeled nucleic acid.
Public/Granted literature
- US20050118621A1 Methods for labeling nucleotides, labeled nucleotides and useful intermediates Public/Granted day:2005-06-02
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