发明授权
US07220569B2 Nucleic acids encoding factor X analogues having a modified protease cleavage site
有权
编码具有修饰的蛋白酶切割位点的因子X类似物的核酸
- 专利标题: Nucleic acids encoding factor X analogues having a modified protease cleavage site
- 专利标题(中): 编码具有修饰的蛋白酶切割位点的因子X类似物的核酸
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申请号: US10407123申请日: 2003-04-04
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公开(公告)号: US07220569B2公开(公告)日: 2007-05-22
- 发明人: Michele Himmelspach , Uwe Schlokat , Friedrich Dorner , Andreas Fisch , Johann Eibl
- 申请人: Michele Himmelspach , Uwe Schlokat , Friedrich Dorner , Andreas Fisch , Johann Eibl
- 申请人地址: AT Vienna
- 专利权人: Baxter Aktiengesellschaft
- 当前专利权人: Baxter Aktiengesellschaft
- 当前专利权人地址: AT Vienna
- 代理机构: Townsend and Townsend and Crew LLP
- 优先权: ATA335/97 19970227
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C07H21/04 ; C12N15/63 ; C12N1/21 ; A61K35/14
摘要:
Nucleic acids encoding factor X analogues are provided that have a modification in the region of the natural Factor Xa activation cleavage site. The modification results in a processing site for a protease not naturally cleaving in this region of the Factor X sequence.
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