Invention Grant
- Patent Title: Bi-cyclic pyrimidine inhibitors of TGFβ
- Patent Title (中): TGFbeta的双环嘧啶抑制剂
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Application No.: US10811428Application Date: 2004-03-26
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Publication No.: US07223766B2Publication Date: 2007-05-29
- Inventor: Sundeep Dugar , Sarvajit Chakravarty , Aurelia Conte , Jonathan Axon , Glenn McEnroe , Alison Murphy
- Applicant: Sundeep Dugar , Sarvajit Chakravarty , Aurelia Conte , Jonathan Axon , Glenn McEnroe , Alison Murphy
- Applicant Address: US CA Fremont
- Assignee: Scios, Inc.
- Current Assignee: Scios, Inc.
- Current Assignee Address: US CA Fremont
- Agency: Morrison & Foerster LLP
- Main IPC: A61K31/517
- IPC: A61K31/517 ; C07D239/70
Abstract:
Compounds in which a pyrimidine nucleus is bridged at the 5 and 6 position and are further substituted at positions 2 and 4 with substituents comprising aromatic moieties are useful in treating subjects with rheumatoid arthritis ameliorated by inhibition of TGFβ activity.
Public/Granted literature
- US20050004143A1 Bi-cyclic pyrimidine inhibitors of TGFbeta Public/Granted day:2005-01-06
Information query
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