发明授权
- 专利标题: Substituted benzodioxepines
- 专利标题(中): 取代苯并二氧杂环庚烯
-
申请号: US10539515申请日: 2003-11-27
-
公开(公告)号: US07253202B2公开(公告)日: 2007-08-07
- 发明人: Timo Heinrich , Henning Böttcher , Kai Schiemann , Günter Hölzemann , Christoph van Amsterdam , Gerd Bartoszyk , Hartmut Greiner , Christoph Seyfried , Michel Brunet , Jean Zeiller , Jean Berthelon
- 申请人: Timo Heinrich , Henning Böttcher , Kai Schiemann , Günter Hölzemann , Christoph van Amsterdam , Gerd Bartoszyk , Hartmut Greiner , Christoph Seyfried , Michel Brunet , Jean Zeiller , Jean Berthelon
- 申请人地址: DE Darmstadt
- 专利权人: Merck Patent GmbH
- 当前专利权人: Merck Patent GmbH
- 当前专利权人地址: DE Darmstadt
- 代理机构: Millen, White, Zelano & Branigan, P.C.
- 优先权: EP02028596 20021220
- 国际申请: PCT/EP03/13373 WO 20031127
- 国际公布: WO2004/058746 WO 20040715
- 主分类号: C07D405/12
- IPC分类号: C07D405/12 ; A61K31/357 ; A61K31/404
摘要:
Benzodioxepines of the formula (I) and physiologically tolerated salts and solvates thereof, in which R1, R2, R3, R4, A, B, a and b have the meanings indicated in claim 1, are ligands of the 5HT1A receptors and/or the 5HT4 receptors with simultaneously strong serotonin reuptake inhibition. They can be employed for the treatment and prophylaxis of various diseases
公开/授权文献
- US20060167078A1 Substituted benzodioxepins 公开/授权日:2006-07-27