发明授权
US07265132B2 Compounds useful as reversible inhibitors of cysteine proteases
有权
可用作半胱氨酸蛋白酶的可逆抑制剂的化合物
- 专利标题： Compounds useful as reversible inhibitors of cysteine proteases
- 专利标题（中）： 可用作半胱氨酸蛋白酶的可逆抑制剂的化合物
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申请号： US10937533申请日： 2004-09-09
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公开(公告)号： US07265132B2公开(公告)日： 2007-09-04
- 发明人: Michel Jose Emmanuel , Leah L. Frye , Eugene R. Hickey , Weimin Liu , Tina Marie Morwick , Denice Mary Spero , David S. Thomson , Yancey David Ward , Erick Richard Roush Young
- 申请人： Michel Jose Emmanuel , Leah L. Frye , Eugene R. Hickey , Weimin Liu , Tina Marie Morwick , Denice Mary Spero , David S. Thomson , Yancey David Ward , Erick Richard Roush Young
- 申请人地址： US CT Ridgefield
- 专利权人： Boehringer Ingelheim Pharmaceuticals Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals Inc.
- 当前专利权人地址： US CT Ridgefield
- 代理商 Michael P. Morris; Mary-Ellen M. Devlin; Anthony P. Bottino
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; C07D211/06 ; C07D211/56
摘要：
Disclosed are cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds
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