Invention Grant
US07276258B2 Herbal extract and compound lupinoside and its analogues as anti-diabetic type II drugs from plant Pueraria tuberosa
失效
草药提取物和化合物lupinoside及其类似物作为来自植物葛根结节的抗糖尿病II型药物
- Patent Title: Herbal extract and compound lupinoside and its analogues as anti-diabetic type II drugs from plant Pueraria tuberosa
- Patent Title (中): 草药提取物和化合物lupinoside及其类似物作为来自植物葛根结节的抗糖尿病II型药物
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Application No.: US10809645Application Date: 2004-03-25
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Publication No.: US07276258B2Publication Date: 2007-10-02
- Inventor: Debleena Dey , Swapan Kumar Mandal , Mohua Mukherjee , Bikash Chandra Pal , Tanushree Biswas , Malabika Datta , Sib Sankar Roy , Arun Bandyopadhyay , Samir Bhattacharya , Bir Bhanu Giri , Santu Bandopadhyay , Aditya Konar
- Applicant: Debleena Dey , Swapan Kumar Mandal , Mohua Mukherjee , Bikash Chandra Pal , Tanushree Biswas , Malabika Datta , Sib Sankar Roy , Arun Bandyopadhyay , Samir Bhattacharya , Bir Bhanu Giri , Santu Bandopadhyay , Aditya Konar
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Madan, Mossman & Sriram, P.C.
- Main IPC: A01N65/00
- IPC: A01N65/00 ; A61N43/04 ; A61K31/70
Abstract:
The present invention relates to a method of preventing and/or treating diabetes type 2, also, it relates to a method of augmenting Glut4 phosphorylation and Glut4 translocation to a target cell membrane to enhance insulin signal in a signal transduction pathway; further, it relates to a simplified and inexpensive process of obtaining extract and thereafter selectively, its active n-butanol fraction and active molecule Lupinoside PA (LPA4), useful in preventing and/or treating diabetes type 2; and lastly, a pharmaceutical composition thereof.
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