发明授权
- 专利标题： Kappa agonist compounds and pharmaceutical formulations thereof
- 专利标题（中）： 卡帕激动剂化合物及其药物制剂
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申请号： US10455545申请日： 2003-06-05
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公开(公告)号： US07294647B2公开(公告)日： 2007-11-13
- 发明人: Lawrence I. Kruse , An-Chih Chang , Diane L. DeHaven-Hudkins , John J. Farrar , Forrest Gaul , Virendra Kumar , Michael Anthony Marella , Alan L. Maycock , Wei Yuan Zhang
- 申请人： Lawrence I. Kruse , An-Chih Chang , Diane L. DeHaven-Hudkins , John J. Farrar , Forrest Gaul , Virendra Kumar , Michael Anthony Marella , Alan L. Maycock , Wei Yuan Zhang
- 申请人地址： US PA Exton
- 专利权人： Adolor Corporation
- 当前专利权人： Adolor Corporation
- 当前专利权人地址： US PA Exton
- 代理机构： Woodcock Washburn LLP
- 主分类号： A01N43/38
- IPC分类号： A01N43/38 ; A01N43/36 ; A01N43/64 ; A61K31/40 ; A61K31/41
摘要：
Compounds having kappa opioid agonist activity, compositions containing them and 5 method of using them as analgesics and pruritic agents are provided.The compounds of formulae I, II, III and IV have the structure: wherein X, X4, X5, X7, X9; R1, R2, R3, R4; and Y, Z and n are as described in the specification.
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