发明授权
- 专利标题： Identifying and testing antisense oligonucleotides that inhibit telomerase reverse transcriptase
- 专利标题（中）： 鉴定和测试抑制端粒酶逆转录酶的反义寡核苷酸
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申请号： US10637443申请日： 2003-08-08
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公开(公告)号： US07297488B2公开(公告)日： 2007-11-20
- 发明人: Thomas R. Cech , Joachim Lingner , Toru Nakamura , Karen B. Chapman , Gregg B. Morin , Calvin B. Harley , William H. Andrews
- 申请人： Thomas R. Cech , Joachim Lingner , Toru Nakamura , Karen B. Chapman , Gregg B. Morin , Calvin B. Harley , William H. Andrews
- 申请人地址： US CA Menlo Park US CO Boulder
- 专利权人： Geron Corporation,The Regents of the University of Colorado
- 当前专利权人： Geron Corporation,The Regents of the University of Colorado
- 当前专利权人地址： US CA Menlo Park US CO Boulder
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C12N15/63 ; C07H21/02 ; C07H21/04
摘要：
This disclosure provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for cancer, and methods of treating telomerase-related conditions, including cancer.
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