发明授权
- 专利标题: Methods for the detection, analysis and isolation of nascent proteins
- 专利标题(中): 新生蛋白的检测,分析和分离方法
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申请号: US10339712申请日: 2003-01-10
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公开(公告)号: US07312060B2公开(公告)日: 2007-12-25
- 发明人: Kenneth J. Rothschild , Sadanand Gite , Jerzy Olejnik , Mark Lim
- 申请人: Kenneth J. Rothschild , Sadanand Gite , Jerzy Olejnik , Mark Lim
- 申请人地址: US MA Watertown
- 专利权人: Ambergen, Inc.
- 当前专利权人: Ambergen, Inc.
- 当前专利权人地址: US MA Watertown
- 代理机构: Medlen & Carroll, LLP
- 主分类号: C07H21/04
- IPC分类号: C07H21/04
摘要:
This invention relates to non-radioactive markers that facilitate the detection and analysis of nascent proteins translated within cellular or cell-free translation systems. Nascent proteins containing these markers can be rapidly and efficiently detected, isolated and analyzed without the handling and disposal problems associated with radioactive reagents. Preferred markers are dipyrrometheneboron difluoride(4,4-difluoro-4-bora-3a,4a-diaza-s-indacene)dyes.
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