发明授权
US07326543B2 Gene encoding protein from merozoite of Babesia caballi, recombinant protein obtained with said gene and use thereof
失效
来自Babesia caballi的裂殖子的基因编码蛋白，用该基因获得的重组蛋白及其用途
- 专利标题： Gene encoding protein from merozoite of Babesia caballi, recombinant protein obtained with said gene and use thereof
- 专利标题（中）： 来自Babesia caballi的裂殖子的基因编码蛋白，用该基因获得的重组蛋白及其用途
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申请号： US10863338申请日： 2004-06-09
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公开(公告)号： US07326543B2公开(公告)日： 2008-02-05
- 发明人: Hiromi Ikadai , Ikuo Igarashi , Naoyoshi Suzuki , Hideyuki Nagasawa , Kozo Fujisaki , Takeshi Mikami
- 申请人： Hiromi Ikadai , Ikuo Igarashi , Naoyoshi Suzuki , Hideyuki Nagasawa , Kozo Fujisaki , Takeshi Mikami
- 申请人地址： JP Obihiro-shi JP Kumamoto-shi
- 专利权人： Takeshi Mikami,Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人： Takeshi Mikami,Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人地址： JP Obihiro-shi JP Kumamoto-shi
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C12P21/04 ; A61K39/002 ; A61K39/015 ; C07K1/00
摘要：
The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In accordance with the present invention, it is possible to stably prepare the 48 kDa protein of rhoptry of Babesia caballi and the gene encoding said protein in a large amount with the recombinant DNA technique. The present invention also provides a method for diagnosing equine babesiasis which comprises either specifically detecting anti-Babesia caballi antibody present in equine blood by using the recombinant protein of present invention as an antigen or detecting the presence of Babesia caballi merozoite in equine blood by using the antibody of the present invention.