发明授权
- 专利标题: Ubiqutin proteases
- 专利标题(中): Ubiqutin蛋白酶
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申请号: US10165231申请日: 2002-06-06
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公开(公告)号: US07329529B2公开(公告)日: 2008-02-12
- 发明人: Rosana Kapeller-Libermann
- 申请人: Rosana Kapeller-Libermann
- 申请人地址: US MA Cambridge
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 主分类号: C12N9/64
- IPC分类号: C12N9/64 ; G01N33/53 ; G01N33/00 ; C12Q1/37 ; C07K14/00 ; C12P21/06 ; C12N15/00 ; C12N5/10 ; C12N1/20 ; C07H21/04
摘要:
The invention provides isolated nucleic acids molecules that encode novel ubiquitin protease polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the ubiquitin protease nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a ubiquitin protease sequence of the invention has been introduced or disrupted. The invention still further provides isolated ubiquitin protease proteins, fusion proteins, antigenic peptides and antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
公开/授权文献
- US20070292845A1 NOVEL UBIQUTIN PROTEASES 公开/授权日:2007-12-20
信息查询
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