发明授权
- 专利标题： Immunoglobulin chimeric monomer-dimer hybrids
- 专利标题（中）： 免疫球蛋白嵌合单体 - 二聚体杂交体
-
申请号： US11029003申请日： 2005-01-05
-
公开(公告)号： US07348004B2公开(公告)日： 2008-03-25
- 发明人: Robert T. Peters , Adam R. Mezo , Daniel S. Rivera , Alan J. Bitonti , Susan C. Low , James Stattel
- 申请人： Robert T. Peters , Adam R. Mezo , Daniel S. Rivera , Alan J. Bitonti , Susan C. Low , James Stattel
- 申请人地址： US MA Waltham
- 专利权人： Syntonix Pharmaceuticals, Inc.
- 当前专利权人： Syntonix Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Waltham
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07K16/00 ; C07K1/00 ; C07K14/00 ; C12P21/08
摘要：
The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
公开/授权文献
- US20050260194A1 Immunoglobulin chimeric monomer-dimer hybrids 公开/授权日：2005-11-24
信息查询
