发明授权
- 专利标题： Early diagnosis of conformational diseases
- 专利标题（中）： 构象疾病的早期诊断
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申请号： US10332370申请日： 2001-06-13
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公开(公告)号： US07351526B2公开(公告)日： 2008-04-01
- 发明人: Claudio Soto , Gabriella Saborio
- 申请人： Claudio Soto , Gabriella Saborio
- 申请人地址： CH Coinsins, Vaud
- 专利权人： Laboratories Serono SA
- 当前专利权人： Laboratories Serono SA
- 当前专利权人地址： CH Coinsins, Vaud
- 代理机构： Browdy and Neimark, PLLC
- 优先权： EP00114650 20000707; EP00127892 20001220; EP01102732 20010207
- 国际申请： PCT/GB01/02584 WO 20010613
- 国际公布： WO02/04954 WO 20020117
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K16/00
摘要：
A method for the diagnosis or detection of conformational diseases by assaying for a marker (the pathogenic conformer) of such diseases in a sample is described, which method comprises a cyclic amplification system to increase the levels of the pathogenic conformer which causes such diseases. In particular, such transmissible conformational diseases may be prion encephalopathies. Assays, diagnostic kits and apparatus based on such methods are also disclosed.
公开/授权文献
- US20050064505A1 Early diagnosis of conformational diseases 公开/授权日：2005-03-24
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