发明授权
- 专利标题: Process for the production of β-amino acids using acylase
- 专利标题(中): 使用酰基转移酶生产β-氨基酸的方法
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申请号: US11198242申请日: 2005-08-08
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公开(公告)号: US07351571B2公开(公告)日: 2008-04-01
- 发明人: Tsuyoshi Nakamatsu , Hisashi Kawasaki , Kunihiko Watanabe , Masakazu Nakazawa , Kunisuke Izawa
- 申请人: Tsuyoshi Nakamatsu , Hisashi Kawasaki , Kunihiko Watanabe , Masakazu Nakazawa , Kunisuke Izawa
- 申请人地址: JP Tokyo
- 专利权人: Ajinomoto Co., Inc.
- 当前专利权人: Ajinomoto Co., Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Cermak Kenealy & Vaidya LLP
- 代理商 Shelly Guest Cermak
- 优先权: JP2004-231306 20040806
- 主分类号: C12N1/20
- IPC分类号: C12N1/20 ; C12P13/04 ; C07H21/04
摘要:
The present invention relates to a Variovorax sp. which produces an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a Burkholderia sp. which produces both an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an S-β-amino acid and an acylase having an asymmetric hydrolysis activity of an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a process for the selective production of an S-, or R-β-amino acid using the above strains.