Invention Grant
![Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity](/docs/US/2008-04-15/US07358250B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity
- Patent Title (中): 吡咯并[2,3-d]嘧啶，其调节ACK1活性
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Application No.: US11169313Application Date: 2005-06-29
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Publication No.: US07358250B2Publication Date: 2008-04-15
- Inventor: Christopher N. Farthing , Paul Faulder , Alexander D. Frenkel , Martin J. Harrison , Xianyun Jiao , Frank Kayser , David J. Kopecky , Jinqian Liu , Sarah E. Lively , Rajiv Sharma , Stephen J. Shuttleworth
- Applicant: Christopher N. Farthing , Paul Faulder , Alexander D. Frenkel , Martin J. Harrison , Xianyun Jiao , Frank Kayser , David J. Kopecky , Jinqian Liu , Sarah E. Lively , Rajiv Sharma , Stephen J. Shuttleworth
- Applicant Address: US CA Thousands Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousands Oaks
- Agency: Foley & Lardner LLP
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D413/10 ; A61P35/04 ; C07F9/02 ; A61K31/519 ; A61K31/5355 ; A61K31/675
![Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity](/abs-image/US/2008/04/15/US07358250B2/abs.jpg.150x150.jpg)
Abstract:
Compounds that modulate the action of ACK1 and LCK, and related compositions methods for treating ACK1- and LCK-mediated diseases are described. In one aspect, the compounds have the general structure: where the values of the substituents are provided herein.
Public/Granted literature
- US20060040965A1 Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity Public/Granted day:2006-02-23
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