Invention Grant
- Patent Title: Quinazolinone compounds with reduced bioaccumulation
- Patent Title (中): 喹唑啉酮化合物具有降低的生物蓄积性
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Application No.: US10993147Application Date: 2004-11-19
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Publication No.: US07368453B2Publication Date: 2008-05-06
- Inventor: Rustum S. Boyce , Jason D. Speake , James Phillips
- Applicant: Rustum S. Boyce , Jason D. Speake , James Phillips
- Applicant Address: US CA Emeryville US NC Research Triangle Park
- Assignee: Chiron Corporation,Glaxo SmithKline
- Current Assignee: Chiron Corporation,Glaxo SmithKline
- Current Assignee Address: US CA Emeryville US NC Research Triangle Park
- Agent Vinit Kathardekar; Joseph P. Meara
- Main IPC: A61K31/517
- IPC: A61K31/517 ; C07D239/72 ; C07D401/12 ; C07D403/12
Abstract:
A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the formula IA and IB. IA and IB have the following structures where Z has the formula shown below and the rest of the variables are defined herein
Public/Granted literature
- US20050192297A1 Quinazolinone compounds with reduced bioaccumulation Public/Granted day:2005-09-01
Information query
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