Input/output interruptions are managed in computing environments that do not use dedicated per-guest interruption hardware to present interruptions. Dispatchable guest programs in the environment receive I/O interruptions directly without hypervisor intervention. This is facilitated by using one or more interruption controls stored in memory and associated with each guest program. For those guest programs that are not currently dispatchable, interruptions can be posted for the guests and notifications to the hypervisor can be aggregated. The hypervisor can then process a plurality of notifications for the plurality of guests in a single invocation.