发明授权
- 专利标题： Detection of specific nitrated markers
- 专利标题（中）： 检测特异性硝化标记物
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申请号： US10507479申请日： 2003-03-12
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公开(公告)号： US07393649B2公开(公告)日： 2008-07-01
- 发明人: Jean-Yves Reginster , Michelle Deberg , Yves Henrotin , Stephan Christgau
- 申请人： Jean-Yves Reginster , Michelle Deberg , Yves Henrotin , Stephan Christgau
- 申请人地址： BG Liege
- 专利权人： Universite de Liege
- 当前专利权人： Universite de Liege
- 当前专利权人地址： BG Liege
- 代理机构： Jacobson Holman PLLC
- 优先权： DKPA200200381 20020313
- 国际申请： PCT/EP03/02559 WO 20030312
- 国际公布： WO03/076946 WO 20030918
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; G01N33/68 ; A61K38/39
摘要：
Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
公开/授权文献
- US20050176081A1 Detection of specific nitrated markers 公开/授权日：2005-08-11
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