- 专利标题: Medical devices having antimicrobial coatings thereon
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申请号: US10287091申请日: 2002-11-04
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公开(公告)号: US07402318B2公开(公告)日: 2008-07-22
- 发明人: Carol Ann Morris , Manal M. Gabriel , Yongxing Qiu , Lynn Cook Winterton , John Martin Lally , Marcia Kay Ash , Fiona Patricia Carney , Courtney Flem Morgan
- 申请人: Carol Ann Morris , Manal M. Gabriel , Yongxing Qiu , Lynn Cook Winterton , John Martin Lally , Marcia Kay Ash , Fiona Patricia Carney , Courtney Flem Morgan
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Sheng-Hsin Hu; Jian Zhou
- 主分类号: A61F13/00
- IPC分类号: A61F13/00
摘要:
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.
公开/授权文献
- US20030117579A1 Medical devices having antimicrobial coatings thereon 公开/授权日:2003-06-26