发明授权
- 专利标题: Method of screening antiplatelet agents
- 专利标题(中): 筛选抗血小板药的方法
-
申请号: US10333844申请日: 2001-10-31
-
公开(公告)号: US07405051B2公开(公告)日: 2008-07-29
- 发明人: Jun Takasaki , Mitsuyuki Matsumoto , Masazumi Kamohara , Tetsu Saito , Takahide Ohishi , Takatoshi Soga
- 申请人: Jun Takasaki , Mitsuyuki Matsumoto , Masazumi Kamohara , Tetsu Saito , Takahide Ohishi , Takatoshi Soga
- 申请人地址: JP Tokyo
- 专利权人: Astellas Pharma Inc.
- 当前专利权人: Astellas Pharma Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 优先权: JP2000-334721 20001101; JP2001-003577 20010111
- 国际申请: PCT/JP01/09534 WO 20011031
- 国际公布: WO02/36631 WO 20020510
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; G01N33/567 ; G01N33/566 ; C12Q1/68 ; C12N5/00 ; C12N5/06 ; C07K1/00
摘要:
A screening tool for an antiplatelet agent wherein the tool is a human ADP receptor P2TAC protein, a variation functionally equivalent thereto, or a homologous protein thereof, and a screening tool for an antiplatelet agent wherein the tool is a transformant which is transformed with an expression vector comprising a DNA encoding the protein and is expressing the polypeptide are disclosed. Further, a method for detecting an ADP receptor P2TAC ligand, antagonist, or agonist by using the screening tool for an antiplatelet agent, and a method for screening an antiplatelet agent by the detecting method are disclosed.
公开/授权文献
- US20030124626A1 Method of screening antiplatelet 公开/授权日:2003-07-03
信息查询
IPC分类: