发明授权
- 专利标题： Modulation of eIF4E expression
- 专利标题（中）： 调节eIF4E表达
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申请号： US10571339申请日： 2004-09-17
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公开(公告)号： US07425544B2公开(公告)日： 2008-09-16
- 发明人: Kenneth Dobie , Eric G. Marcusson , Eric E. Swayze , Balkrishen Bhat , Jeremy Richard Graff
- 申请人： Kenneth Dobie , Eric G. Marcusson , Eric E. Swayze , Balkrishen Bhat , Jeremy Richard Graff
- 申请人地址： US IN Indianapolis US CA Carlsbad
- 专利权人： Eli Lilly and Company,ISIS Pharmaceuticals, Inc.
- 当前专利权人： Eli Lilly and Company,ISIS Pharmaceuticals, Inc.
- 当前专利权人地址： US IN Indianapolis US CA Carlsbad
- 代理商 Charles E. Cohen
- 国际申请： PCT/US2004/030436 WO 20040917
- 国际公布： WO2005/028628 WO 20050331
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N5/00 ; C12Q1/68
摘要：
Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E. Methods of using these compounds for modulation of eIF4E expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E are provided.
公开/授权文献
- US20070066549A1 Modulation of elf4e expression 公开/授权日：2007-03-22
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