发明授权
- 专利标题: Benzimidazole compound
- 专利标题(中): 苯并咪唑化合物
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申请号: US11520838申请日: 2006-09-14
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公开(公告)号: US07425634B2公开(公告)日: 2008-09-16
- 发明人: Shuhei Miyazawa , Masanobu Shinoda , Tetsuya Kawahara , Nobuhisa Watanabe , Hitoshi Harada , Daisuke Iida , Hiroki Terauchi , Junichi Nagakawa , Hideaki Fujisaki , Atsuhiko Kubota , Masato Ueda
- 申请人: Shuhei Miyazawa , Masanobu Shinoda , Tetsuya Kawahara , Nobuhisa Watanabe , Hitoshi Harada , Daisuke Iida , Hiroki Terauchi , Junichi Nagakawa , Hideaki Fujisaki , Atsuhiko Kubota , Masato Ueda
- 申请人地址: JP Tokyo
- 专利权人: Eisai R&D Management Co., Ltd.
- 当前专利权人: Eisai R&D Management Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch and Birch, LLP
- 优先权: JP2005-117643 20050415
- 主分类号: C07D401/12
- IPC分类号: C07D401/12
摘要:
An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability.Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.
公开/授权文献
- US20070010542A1 Benzimidazole compound 公开/授权日:2007-01-11
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