发明授权
US07427390B2 Radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy
失效
放射性卤代苯甲酰胺衍生物及其在肿瘤诊断和肿瘤治疗中的应用
- 专利标题: Radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy
- 专利标题(中): 放射性卤代苯甲酰胺衍生物及其在肿瘤诊断和肿瘤治疗中的应用
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申请号: US11076023申请日: 2005-03-10
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公开(公告)号: US07427390B2公开(公告)日: 2008-09-23
- 发明人: Matthias Friebe , Peter Muschick , Andreas Huth
- 申请人: Matthias Friebe , Peter Muschick , Andreas Huth
- 申请人地址: DE Berlin
- 专利权人: Schering AG
- 当前专利权人: Schering AG
- 当前专利权人地址: DE Berlin
- 代理机构: Millen, White, Zelano & Branigan, P.C.
- 优先权: DE102004011720 20040310
- 主分类号: A61K51/00
- IPC分类号: A61K51/00 ; A61M36/14
摘要:
This invention relates to new radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy. The radiohalogenated benzamide derivatives according to the invention exhibit novel and especially advantageous properties, in particular with respect to tumor concentration and retardation, liver concentration and blood accumulation. The radiation-therapy doses to be achieved in the tumor, compared to healthy body tissue, are advantageous for the compounds according to the invention.
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