发明授权
US07432379B2 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists
失效
取代的吡唑衍生物和相关化合物作为缓激肽B1受体拮抗剂
- 专利标题： Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists
- 专利标题（中）： 取代的吡唑衍生物和相关化合物作为缓激肽B1受体拮抗剂
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申请号： US10837231申请日： 2004-04-30
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公开(公告)号： US07432379B2公开(公告)日： 2008-10-07
- 发明人: Jay S. Tung , Albert W. Garofalo , Michael A. Pleiss , Jing Wu , David W. G. Wone , Ashley C. Guinn , Darren B. Dressen , R. Jeffrey Neitz , Jennifer Marugg , Martin Neitzel
- 申请人： Jay S. Tung , Albert W. Garofalo , Michael A. Pleiss , Jing Wu , David W. G. Wone , Ashley C. Guinn , Darren B. Dressen , R. Jeffrey Neitz , Jennifer Marugg , Martin Neitzel
- 申请人地址： US CA South San Francisco
- 专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Foley & Lardner LLP
- 主分类号： C07D401/12
- IPC分类号： C07D401/12
摘要：
Disclosed are compounds that are bradykinin B1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B1 receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.
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