发明授权
- 专利标题： Process for utilizing epitopes recognized by natural antibodies
- 专利标题（中）： 利用天然抗体识别的表位的方法
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申请号： US10795676申请日： 2004-03-08
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公开(公告)号： US07439051B2公开(公告)日： 2008-10-21
- 发明人: Alexander V. Sokoloff , Jon A. Wolff
- 申请人： Alexander V. Sokoloff , Jon A. Wolff
- 申请人地址： US WI Madison
- 专利权人： Mirus Bio Corporation
- 当前专利权人： Mirus Bio Corporation
- 当前专利权人地址： US WI Madison
- 代理商 Kirk Ekena; Mark K. Johnson
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12N15/00 ; C12Q1/70
摘要：
The present invention relates to compositions and methods for the selection and use of surface exposed epitopes. The present invention includes in vivo and in vitro phage peptide diplay methods for the identification and selection of peptides and peptide associated factors with desired properties (e.g., targeting specificity, stability, etc.). The present invention further provides methods and compositions for the isolation and identification of peptide-specific antibodies. The present invention also includes methods and compositions employing nuclear localization signals for enhanced nuclear transport and expression of DNA.