发明授权
- 专利标题: DNA encoding hydroxylase
- 专利标题(中): 编码羟化酶的DNA
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申请号: US11352308申请日: 2006-02-13
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公开(公告)号: US07470528B2公开(公告)日: 2008-12-30
- 发明人: Hirofumi Endo , Yoshiyuki Yonetani , Hiroshi Mizoguchi , Shin-ichi Hashimoto , Akio Ozaki
- 申请人: Hirofumi Endo , Yoshiyuki Yonetani , Hiroshi Mizoguchi , Shin-ichi Hashimoto , Akio Ozaki
- 申请人地址: JP Tokyo
- 专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Greenblum & Bernstein, P.L.C.
- 优先权: JP11-21707 19990129
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; C12N5/10 ; C12N1/21 ; C12P21/00 ; C07H21/00 ; C12N9/02 ; C07K14/00
摘要:
The present invention relates to a protein derived from a microorganism belonging to the genus Bacillus, which has an activity of hydroxylating a compound represented by the formula (I-a): wherein R1 represents a hydrogen atom, a substituted or unsubstituted alkyl, or an alkali metal, and R2 represents a substituted or unsubstituted alkyl or a substituted or unsubstituted aryl, or a ring-closed lactone form thereof; a DNA encoding the protein; and a recombinant DNA comprising the DNA.
公开/授权文献
- US20060154348A1 Process for producing HMG-CoA reductase inhibitors 公开/授权日:2006-07-13
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