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US07473430B2 Cancer cell targeting gene delivery method 有权
癌细胞靶向基因递送方法

Cancer cell targeting gene delivery method
摘要:
The inventive chimeric ligand in the form of a fusion polypeptide of a single-chain antibody specific for Tag-72 surface antigen and GaLV envelope glycoprotein shows high transduction efficiency to cancer cells, specifically infects target cells and efficiently delivers a therapeutic gene. Accordingly, the inventive chimeric ligand can be effectively used for gene therapy to inhibit tumor growth and metastasis.
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