发明授权
- 专利标题： Liposome for incorporating large amounts of hydrophobic substances
- 专利标题（中）： 用于掺入大量疏水物质的脂质体
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申请号： US10624362申请日： 2003-07-23
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公开(公告)号： US07485320B2公开(公告)日： 2009-02-03
- 发明人: Pei Kan , Ae-June Wang , Won-Ko Chen , Chih-Wan Tsao
- 申请人： Pei Kan , Ae-June Wang , Won-Ko Chen , Chih-Wan Tsao
- 申请人地址： TW Hsinchu
- 专利权人： Industrial Technology Research Institute
- 当前专利权人： Industrial Technology Research Institute
- 当前专利权人地址： TW Hsinchu
- 代理机构： Rabin & Berdo, P.C.
- 优先权： TW89119777A 20000925
- 主分类号： A61K31/07
- IPC分类号： A61K31/07 ; A61K31/135 ; A61K31/165 ; A61K31/21 ; A61K31/215 ; A61K31/235 ; A61K31/24 ; A61K31/335 ; A61K31/40 ; A61K31/44 ; A61K31/66 ; A61K31/685
摘要：
A liposome formulation for stably incorporating high content of hydrophobic substance is disclosed. The liposome includes two phospholipids with different phase transition temperatures such as saturated and unsaturated phosphatidyl cholines, hydrophobic substances, cholesterol, cholesterol derivatives, antioxidant and hydrophilic polymer-modified lipids such as MPEG-DSPE.
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