发明授权
US07488479B2 Nucleic acid and corresponding protein entitled 125P5C8 useful in treatment and detection of cancer
失效
核酸和相应的蛋白质125P5C8可用于治疗和检测癌症
- 专利标题： Nucleic acid and corresponding protein entitled 125P5C8 useful in treatment and detection of cancer
- 专利标题（中）： 核酸和相应的蛋白质125P5C8可用于治疗和检测癌症
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申请号： US10099460申请日： 2002-03-13
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公开(公告)号： US07488479B2公开(公告)日： 2009-02-10
- 发明人: Mary Faris , Pia M. Challita-Eid , Rene S. Hubert , Daniel E. H. Afar , Arthur B. Raitano , Wangmao Ge , Robert Kendall Morrison , Karen Jane Meyrick Morrison , Aya Jakobovits
- 申请人： Mary Faris , Pia M. Challita-Eid , Rene S. Hubert , Daniel E. H. Afar , Arthur B. Raitano , Wangmao Ge , Robert Kendall Morrison , Karen Jane Meyrick Morrison , Aya Jakobovits
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
A novel gene (designated 125P5C8) and its encoded protein, and variants thereof, are described wherein 125P5C8 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 125P5C8 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 125P5C8 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 125P5C8 can be used in active or passive immunization.