发明授权
US07514442B2 Trisubstituted 4-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
有权
三取代的4-氨基吡唑并嘧啶作为细胞周期蛋白依赖性激酶抑制剂
- 专利标题： Trisubstituted 4-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
- 专利标题（中）： 三取代的4-氨基吡唑并嘧啶作为细胞周期蛋白依赖性激酶抑制剂
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申请号： US11395676申请日： 2006-03-31
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公开(公告)号： US07514442B2公开(公告)日： 2009-04-07
- 发明人: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer , Ronald J. Doll , Viyyoor M. Girijavallabhan , Carmen S. Alvarez , Tin Yau Chan , Chad Knutson , Vincent Madison , Thierry O. Fischmann , Lawrence W. Dillard , Vinh D. Tran , Zhen Min He , Ray Anthony James , Haengsoon Park
- 申请人： Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer , Ronald J. Doll , Viyyoor M. Girijavallabhan , Carmen S. Alvarez , Tin Yau Chan , Chad Knutson , Vincent Madison , Thierry O. Fischmann , Lawrence W. Dillard , Vinh D. Tran , Zhen Min He , Ray Anthony James , Haengsoon Park
- 申请人地址： US NJ Kenilworth US NJ Cranbury
- 专利权人： Schering Corporation,Pharmacopeia, Inc.
- 当前专利权人： Schering Corporation,Pharmacopeia, Inc.
- 当前专利权人地址： US NJ Kenilworth US NJ Cranbury
- 代理商 Palaiyur S. Kalyanaraman; Serena Farquharson-Torres
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D487/04 ; A61P35/04
摘要：
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
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