发明授权
- 专利标题： Phenyl substituted carboxylic acids
- 专利标题（中）： 苯基取代的羧酸
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申请号： US10835924申请日： 2004-04-30
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公开(公告)号： US07524878B2公开(公告)日： 2009-04-28
- 发明人: Darren Whitehouse , Shaojing Hu , Haiquan Fang , Michael C. Van Zandt
- 申请人： Darren Whitehouse , Shaojing Hu , Haiquan Fang , Michael C. Van Zandt
- 申请人地址： US CT Branford
- 专利权人： The Institute for Pharmaceuticals Discovery LLC
- 当前专利权人： The Institute for Pharmaceuticals Discovery LLC
- 当前专利权人地址： US CT Branford
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： A61K31/341
- IPC分类号： A61K31/341 ; A61K31/404 ; C07D209/04 ; C07D307/79
摘要：
Disclosed are compounds and pharmaceutically acceptable salts of formula (A): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of the invention include inhibitors of Protein tyrosine phosphatases, in particular Protein tyrosine phosphatase-1B (PTP-1B), that are useful in the treatment of diabetes and other PTP mediated diseases, such as cancer, neurodegenerative diseases and the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
公开/授权文献
- US20050004369A1 Phenyl substituted carboxylic acids 公开/授权日：2005-01-06
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