发明授权
US07534338B2 Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization(MALDI) mass spectrometry (MS)
失效
用于化学分析的分析物浓缩和纯化的方法和装置，包括基质辅助激光解吸/电离（MALDI）质谱（MS）
- 专利标题： Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization(MALDI) mass spectrometry (MS)
- 专利标题（中）： 用于化学分析的分析物浓缩和纯化的方法和装置，包括基质辅助激光解吸/电离（MALDI）质谱（MS）
-
申请号： US10963336申请日： 2004-10-12
-
公开(公告)号： US07534338B2公开(公告)日： 2009-05-19
- 发明人: Dean Hafeman , Kilian Dill , James B. Harkins , Richard M. Caprioli , Jeremy Norris , Nathan S. Lewis , Daniel Kuban , Charles E. Witkowski, II
- 申请人： Dean Hafeman , Kilian Dill , James B. Harkins , Richard M. Caprioli , Jeremy Norris , Nathan S. Lewis , Daniel Kuban , Charles E. Witkowski, II
- 申请人地址： US TN Knoxville
- 专利权人： Protein Discovery, Inc.
- 当前专利权人： Protein Discovery, Inc.
- 当前专利权人地址： US TN Knoxville
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： H01J49/04
- IPC分类号： H01J49/04
摘要：
Analytical methods and devices are disclosed for separating low abundance analytes by electrophoretically driving the analytes through a sieving matrix to first remove high molecular weight species. Subsequently the remaining low abundance analytes are electrophoretically focused onto a capture membrane where the analytes become bound within a small capture site. After this step the capture membrane may be allowed to dry and then attached to a conductive MALDI sample plate.
公开/授权文献
信息查询
