发明授权
- 专利标题: Condensed heterocyclic pyrazole derivatives as kinase inhibitors
- 专利标题(中): 缩合杂环吡唑衍生物作为激酶抑制剂
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申请号: US10522250申请日: 2003-07-11
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公开(公告)号: US07541378B2公开(公告)日: 2009-06-02
- 发明人: Roberto Tonani , Simona Bindi , Daniele Fancelli , Valeria Pittala′ , Mario Varasi
- 申请人: Roberto Tonani , Simona Bindi , Daniele Fancelli , Valeria Pittala′ , Mario Varasi
- 申请人地址: IT Rome
- 专利权人: Pfizer Italia S.r.l.
- 当前专利权人: Pfizer Italia S.r.l.
- 当前专利权人地址: IT Rome
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 国际申请: PCT/EP03/07531 WO 20030711
- 国际公布: WO2004/013146 WO 20040212
- 主分类号: A61K31/4162
- IPC分类号: A61K31/4162 ; C07D231/00
摘要:
Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer.