发明授权
- 专利标题： Azabicyclo derivatives as muscarinic receptor antagonists
- 专利标题（中）： 偶氮二环衍生物作为毒蕈碱受体拮抗剂
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申请号： US10520572申请日： 2003-04-11
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公开(公告)号： US07544708B2公开(公告)日： 2009-06-09
- 发明人: Mohammad Salman , Anita Mehta , Pakala Kumara Savithru Sarma , Shankar Jayram Shetty , Sankaranarayanan Dharmarajan , Naresh Kumar , Arundutt Vishwanatham Silamkoti , Anita Chugh
- 申请人： Mohammad Salman , Anita Mehta , Pakala Kumara Savithru Sarma , Shankar Jayram Shetty , Sankaranarayanan Dharmarajan , Naresh Kumar , Arundutt Vishwanatham Silamkoti , Anita Chugh
- 申请人地址： IN Gugaon
- 专利权人： Ranbaxy Laboratories Limited
- 当前专利权人： Ranbaxy Laboratories Limited
- 当前专利权人地址： IN Gugaon
- 代理商 George E. Heibel, Esq.
- 优先权： WOPCT/IB02/02663 20020708
- 国际申请： PCT/IB03/01367 WO 20030411
- 国际公布： WO2004/005252 WO 20040115
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; C07D209/44
摘要：
This invention generally relates to muscarinic receptor antagonists which are useful, among other uses, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. Specifically, the invention relates to derivatives of azabicyclo compounds, including, for example, 6-substituted azabicyclo[3.1.0] hexanes, and 2,4,6-trisubstituted derivatives. The invention also relates to pharmaceutical compositions containing the compounds and the methods of treating the diseases mediated through muscarinic receptors.