Invention Grant
- Patent Title: Methods and compositions for impairing multiplication of HIV-1
- Patent Title (中): 减少HIV-1增殖的方法和组合物
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Application No.: US11353293Application Date: 2006-02-13
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Publication No.: US07563437B2Publication Date: 2009-07-21
- Inventor: Roland Carlsson , Elisabeth Sonesson , Yvonne Stenberg , Leif Strandberg , Gideon Goldstein
- Applicant: Roland Carlsson , Elisabeth Sonesson , Yvonne Stenberg , Leif Strandberg , Gideon Goldstein
- Applicant Address: US NJ Short Hills
- Assignee: Thymon, LLC
- Current Assignee: Thymon, LLC
- Current Assignee Address: US NJ Short Hills
- Agency: Howson & Howson LLP
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
A single isolated antibody or antibody fragment thereof binds to multiple variant sequences within an epitope of HIV-1 Tat protein displayed in multiple strains and subtypes of HIV-1. This “pan-epitope” antibody is useful in therapeutic and prophylactic compositions and treatments of HIV-1 infection, regardless of strain. This pan-epitope antibody is useful in assays for the detection of levels of HIV-1 based on a measurement of the amount of Tat protein in a biological sample.
Public/Granted literature
- US20060211108A1 Methods and compositions for impairing multiplication of HIV-1 Public/Granted day:2006-09-21
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