-
1.发明申请PEPTIDE-BASED PASSIVE IMMUNIZATION THERAPY FOR THE TREATMENT OF ATHEROSCLEROSIS 审中-公开基于肽的被动免疫治疗治疗甲状腺功能亢进公开(公告)号：US20120070426A1
公开(公告)日：2012-03-22
申请号：US13272297
申请日：2011-10-13
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
IPC分类号： A61K39/395 , C12P21/02 , C40B30/04 , C07K16/18 , A61P9/10
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
2.发明授权公开(公告)号：US07601353B2
公开(公告)日：2009-10-13
申请号：US11323123
申请日：2005-12-30
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
IPC分类号： A61K39/395 , C07K16/00
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
公开(公告)号：US20060211108A1
公开(公告)日：2006-09-21
申请号：US11353293
申请日：2006-02-13
CPC分类号： C07K16/1072 , C07K2317/92
摘要： A single isolated antibody or antibody fragment thereof binds to multiple variant sequences within an epitope of HIV-1 Tat protein displayed in multiple strains and subtypes of HIV-1. This “pan-epitope” antibody is useful in therapeutic and prophylactic compositions and treatments of HIV-1 infection, regardless of strain. This pan-epitope antibody is useful in assays for the detection of levels of HIV-1 based on a measurement of the amount of Tat protein in a biological sample.
-
公开(公告)号：US20050287137A1
公开(公告)日：2005-12-29
申请号：US11167872
申请日：2005-06-27
申请人： Patrick Dhaese , Pascal Mettens , Rene Meykens , Philippe Monteyne , Torbjorn Schiott , Leif Strandberg
发明人： Patrick Dhaese , Pascal Mettens , Rene Meykens , Philippe Monteyne , Torbjorn Schiott , Leif Strandberg
IPC分类号： A61K39/395 , C07K16/18 , C07K16/44
CPC分类号： C07K16/18 , C07K2317/622
摘要： The present invention relates to novel therapies and treatments of atherosclerotic diseases. Accordingly there is provided, methods of treating or preventing atherosclerosis by passive vaccination through administration to a patient of a fully human antibody that is capable of binding to the specific fragments of ApoCIII. Specific human monoclonal antibodies and their use in therapy of atherosclerosis is provided. There is further provided the use of the antibodies of the present invention in medicine.
摘要翻译： 本发明涉及动脉粥样硬化疾病的新疗法和治疗。 因此，提供了通过向能够结合到ApoCIII的特异性片段的完全人抗体的患者施用被动接种来治疗或预防动脉粥样硬化的方法。 提供特异性人单克隆抗体及其在治疗动脉粥样硬化中的应用。 还提供了本发明的抗体在医药中的用途。
-
5.发明授权公开(公告)号：US08114966B2
公开(公告)日：2012-02-14
申请号：US12258745
申请日：2008-10-27
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
公开(公告)号：US07563437B2
公开(公告)日：2009-07-21
申请号：US11353293
申请日：2006-02-13
IPC分类号： A61K39/395
CPC分类号： C07K16/1072 , C07K2317/92
摘要： A single isolated antibody or antibody fragment thereof binds to multiple variant sequences within an epitope of HIV-1 Tat protein displayed in multiple strains and subtypes of HIV-1. This “pan-epitope” antibody is useful in therapeutic and prophylactic compositions and treatments of HIV-1 infection, regardless of strain. This pan-epitope antibody is useful in assays for the detection of levels of HIV-1 based on a measurement of the amount of Tat protein in a biological sample.
摘要翻译： 单个分离的抗体或其抗体片段结合HIV-1多重菌株和亚型中显示的HIV-1 Tat蛋白的表位内的多个变体序列。 这种“泛表位”抗体可用于HIV-1感染的治疗和预防组合物和治疗，不管应变如何。 该泛表位抗体可用于基于生物样品中Tat蛋白量的测量来检测HIV-1水平的测定中。
-
公开(公告)号：US07521046B2
公开(公告)日：2009-04-21
申请号：US11928221
申请日：2007-10-30
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
IPC分类号： A61K39/395 , A61K39/40 , C07K1/00
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
公开(公告)号：US07468183B2
公开(公告)日：2008-12-23
申请号：US10679032
申请日：2003-10-03
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
IPC分类号： A61K39/395 , A61K39/40 , C07K1/00
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
9.发明申请公开(公告)号：US20070098723A1
公开(公告)日：2007-05-03
申请号：US11323123
申请日：2005-12-30
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
IPC分类号： A61K39/395
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
10.发明申请公开(公告)号：US20090155258A1
公开(公告)日：2009-06-18
申请号：US12258745
申请日：2008-10-27
申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
发明人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
IPC分类号： A61K39/395 , C40B30/04 , C12P21/02 , C07K16/18
CPC分类号： C07K14/775 , A61K2039/505 , C07K16/18 , C07K2317/21 , C07K2317/622
摘要： The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
摘要翻译： 本发明涉及用于治疗或预防动脉粥样硬化的被动免疫，其使用针对至少一种载脂蛋白B的氧化片段的分离的人抗体制造用于通过被动免疫治疗或预防性治疗动脉粥样硬化的药物组合物，以及 制备这种抗体的方法，以及使用这种抗体治疗哺乳动物，优选人的方法以提供被动免疫。
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.018 秒)