Invention Grant
US07579360B2 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
有权
三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
- Patent Title: Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
- Patent Title (中): 三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
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Application No.: US11448947Application Date: 2006-06-07
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Publication No.: US07579360B2Publication Date: 2009-08-25
- Inventor: James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
- Applicant: James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Terence J. Bogie
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D513/02 ; C07D515/02
Abstract:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.
Public/Granted literature
- US20060287357A1 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors Public/Granted day:2006-12-21
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