发明授权
- 专利标题： Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
- 专利标题（中）： 肠球菌粪肠球菌，屎肠球菌等细菌溶菌酶
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申请号： US11439846申请日： 2006-05-24
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公开(公告)号： US07582291B2公开(公告)日： 2009-09-01
- 发明人: Pauline Yoong , Raymond Schuch , Daniel Nelson , Vincent A. Fischetti
- 申请人： Pauline Yoong , Raymond Schuch , Daniel Nelson , Vincent A. Fischetti
- 申请人地址： US NY New York
- 专利权人： The Rockefeller University
- 当前专利权人： The Rockefeller University
- 当前专利权人地址： US NY New York
- 代理机构： Brinks Hofer Gilson & Lione
- 主分类号： A61K38/48
- IPC分类号： A61K38/48 ; A01N63/00 ; C12P21/04 ; C12N9/00 ; C12N7/00
摘要：
The present disclosure relates to bacteriophage lysins useful for the reduction of certain bacterial populations, including methods and compositions for the treatment of various bacterial infections. For example, bacteriophage lysins were isolated and shown to effectively kill various bacteria, including both E. faecalis and E. faecium (including vancomycin resistant strains), as well as other human pathogens.