发明授权
US07595312B2 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions
有权
选择的CGRP拮抗剂，其制备方法及其作为药物组合物的用途
- 专利标题： Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions
- 专利标题（中）： 选择的CGRP拮抗剂，其制备方法及其作为药物组合物的用途
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申请号： US10687262申请日： 2003-10-16
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公开(公告)号： US07595312B2公开(公告)日： 2009-09-29
- 发明人: Klaus Rudolf , Stephan Georg Mueller , Dirk Stenkamp , Philipp Lustenberger , Alexander Dreyer , Eckhart Bauer , Marcus Schindler , Kirsten Arndt , Henri Doods
- 申请人： Klaus Rudolf , Stephan Georg Mueller , Dirk Stenkamp , Philipp Lustenberger , Alexander Dreyer , Eckhart Bauer , Marcus Schindler , Kirsten Arndt , Henri Doods
- 申请人地址： DE Ingelheim
- 专利权人： Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： DE Ingelheim
- 代理商 Michael P. Morris; Mary-Ellen M. Devlin; Alan R. Stempel
- 优先权： DE10250080 20021025
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D401/14
摘要：
The present invention relates to CGRP antagonists of general formula wherein A, U, V, W, X and R1 to R3 are defined as in claim 1, the tautomers, diastereomers, enantiomers, hydrates, mixtures thereof and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.
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