发明授权
- 专利标题： Peptide-based passive immunization therapy for treatment of atherosclerosis
- 专利标题（中）： 基于肽的被动免疫治疗动脉粥样硬化
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申请号： US11323123申请日： 2005-12-30
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公开(公告)号： US07601353B2公开(公告)日： 2009-10-13
- 发明人: Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
- 申请人： Jan Nilsson , Roland Carlsson , Jenny Bengtsson , Leif Strandberg
- 申请人地址： SE Lund
- 专利权人： Forskarpatent I SYD AB
- 当前专利权人： Forskarpatent I SYD AB
- 当前专利权人地址： SE Lund
- 代理机构： Gauthier & Connors LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00
摘要：
The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
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