发明授权
US07605005B2 Method of screening for agents that modulate Tysnd1 level or activity in a cell.
失效
筛选调节细胞中Tysnd1水平或活性的试剂的方法。
- 专利标题: Method of screening for agents that modulate Tysnd1 level or activity in a cell.
- 专利标题(中): 筛选调节细胞中Tysnd1水平或活性的试剂的方法。
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申请号: US12000158申请日: 2007-12-10
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公开(公告)号: US07605005B2公开(公告)日: 2009-10-20
- 发明人: Igor Kurochkin , Christian Schoenbach , Yasushi Okazaki
- 申请人: Igor Kurochkin , Christian Schoenbach , Yasushi Okazaki
- 申请人地址: JP Wako-shi JP Iruma-gun
- 专利权人: Riken,Saitama Medical University
- 当前专利权人: Riken,Saitama Medical University
- 当前专利权人地址: JP Wako-shi JP Iruma-gun
- 代理机构: Edwards Angell Palmer & Dodge LLP
- 优先权: JP2005-169380 20050609
- 主分类号: G01N33/68
- IPC分类号: G01N33/68 ; C07K16/40
摘要:
The invention relates to a pharmaceutical composition for treating or diagnosing a disorder associated with production of peroxisome in a cell, comprising a polypeptide which has cysteine protease activity and directly processes peroxisomal enzymes targeted by PTS1 or PTS2 signals. Preferably, the polypeptide is encoded by Tysnd1.
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