发明授权
- 专利标题： Macrocyclic lactams and pharmaceutical use thereof
- 专利标题（中）： 大环内酰胺及其药物用途
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申请号： US10577260申请日： 2004-11-04
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公开(公告)号： US07612055B2公开(公告)日： 2009-11-03
- 发明人: Yves Auberson , Claudia Betschart , Ralf Glatthar , Kurt Laumen , Rainer Machauer , Marina Tintelnot-Blomley , Thomas J. Troxler , Siem Jacob Veenstra
- 申请人： Yves Auberson , Claudia Betschart , Ralf Glatthar , Kurt Laumen , Rainer Machauer , Marina Tintelnot-Blomley , Thomas J. Troxler , Siem Jacob Veenstra
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理机构： Foley & Lardner LLP
- 优先权： GB0325830.8 20031105
- 国际申请： PCT/EP2004/012497 WO 20041104
- 国际公布： WO2005/049585 WO 20050602
- 主分类号： A01N43/00
- IPC分类号： A01N43/00 ; A61K31/33 ; C07D245/00
摘要：
The present invention relates to novel macrocyclic compounds of the formula wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as pharmaceuticals and to pharmaceutical compositions comprising them.
公开/授权文献
- US20070072792A1 Macrocyclic lactams and pharmaceutical use thereof 公开/授权日：2007-03-29