发明授权
- 专利标题： Methods for purifying adeno-associated virus
- 专利标题（中）： 纯化腺相关病毒的方法
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申请号： US11372552申请日： 2006-03-09
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公开(公告)号： US07625570B1公开(公告)日： 2009-12-01
- 发明人: David V. Schaffer , Joshua N. Leonard
- 申请人： David V. Schaffer , Joshua N. Leonard
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Bozicevic, Field & Francis LLP
- 代理商 Paula A. Borden
- 主分类号： A61K39/23
- IPC分类号： A61K39/23 ; C07K2/00
摘要：
The present invention provides methods of purifying adeno-associated virus (AAV) from compositions comprising AAV and at least a second, non-AAV; and methods for selectively inactivating a non-adeno-associated virus (non-AAV) in a liquid composition comprising AAV and the non-AAV. The methods generally involve subjecting the composition to hydrostatic pressure such that the non-AAV is selectively inactivated.
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