发明授权
US07670603B2 Human DNAX toll-like receptor 4 proteins, related reagents and methods
有权
人类DNAX toll样受体4蛋白,相关试剂和方法
- 专利标题: Human DNAX toll-like receptor 4 proteins, related reagents and methods
- 专利标题(中): 人类DNAX toll样受体4蛋白,相关试剂和方法
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申请号: US12100088申请日: 2008-04-09
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公开(公告)号: US07670603B2公开(公告)日: 2010-03-02
- 发明人: Gerard T. Hardiman , Fernando L. Rock , J. Fernando Bazan , Robert A. Kastelein , Stephen W. K. Ho , Yong-Jun Liu
- 申请人: Gerard T. Hardiman , Fernando L. Rock , J. Fernando Bazan , Robert A. Kastelein , Stephen W. K. Ho , Yong-Jun Liu
- 申请人地址: US NJ Kenilworth
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 当前专利权人地址: US NJ Kenilworth
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12N15/09 ; C12P21/06 ; C07K14/47
摘要:
Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.
公开/授权文献
- US20080199477A1 HUMAN RECEPTOR PROTEINS; RELATED REAGENTS AND METHODS 公开/授权日:2008-08-21
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