发明授权
- 专利标题： Ureas as factor Xa inhibitors
- 专利标题（中）： 尿素作为因子Xa抑制剂
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申请号： US11298317申请日： 2005-12-07
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公开(公告)号： US07678913B2公开(公告)日： 2010-03-16
- 发明人: Yonghong Song , Bing-Yan Zhu , Shumei Wang , Chhaya Bhakta , Robert M. Scarborough
- 申请人： Yonghong Song , Bing-Yan Zhu , Shumei Wang , Chhaya Bhakta , Robert M. Scarborough
- 申请人地址： US CA South San Francisco
- 专利权人： Portola Pharmaceuticals, Inc.
- 当前专利权人： Portola Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： A61K31/48
- IPC分类号： A61K31/48 ; C07D207/40 ; C07D215/38
摘要：
The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
公开/授权文献
- US20060160821A1 Ureas as factor Xa inhibitors 公开/授权日：2006-07-20